Semler Scientific Doubles Down on Bitcoin—Now Holds 4,264 BTC in Corporate Treasury

Another healthcare player bets big on digital gold—because apparently, saving lives wasn’t volatile enough.

The move makes Semler one of the few public companies allocating more to crypto than R&D. Priorities, right?

With this latest purchase, their Bitcoin stash now rivals the reserves of some small nations. Just don’t ask about the carbon footprint.

Semler Scientific, a Nasdaq-listed medical technology and software company based in California, has acquired a significant amount of Bitcoin (BTC). The company acquired an additional 455 BTC — its third-largest purchase since adopting a Bitcoin standard roughly one year ago.

Semler Buys Millions More In Bitcoin

According to the May 23 8-K filing, Semler Scientific spent $50 million on 455 BTC between May 13 and May 22, 2025, at an average purchase price of $109,801 per coin. The company bought the bitcoin using proceeds from its $500 million at-the-market offering program. The company has issued 3,003,488 shares under its April 15 $500 million ATM program, raking in $114.8 million.

Semler now holds a total of 4,264 BTC, valued at roughly $474.4 million. It bought the BTC for an aggregate of $390 million at an average cost basis of $91,471. 

The medical device company has been aggressively purchasing Bitcoin since last year, mirroring the playbook pioneered by Strategy (formerly MicroStrategy) and its Chairman and renowned Bitcoin supporter, Michael Saylor. 

Semler’s BTC Yield has jumped to 25.8% in 2025. BTC yield, a performance indicator popularized by Saylor and Strategy, refers to the ratio of a company’s Bitcoin holdings and its assumed diluted shares outstanding.

At 4,264 BTC, the company’s Bitcoin treasury ranks 13th in size among publicly traded companies, according to BitcoinTreasuries data.

Corporate Treasury Boom

Software intelligence company Strategy started buying BTC in 2020 at the behest of former CEO Michael Saylor. Since then, the company has amassed a  576,230 BTC stash, worth approximately $62 million at current prices.

There are now over 70 firms that have incorporated a Bitcoin treasury, with Cantor Fitzgerald, SoftBank, Bitfinex, and Tether recently announcing the forthcoming launch of a $3.6 billion Bitcoin venture, Twenty One.

Other companies, including Japanese investment firm Metaplanet, have also followed in Strategy’s footsteps and continue stacking the world’s oldest and largest cryptocurrency.